For the first time, it has been shown that an intensively active lifestyle can completely prevent bad diets from impairing sexual function, says a Johns Hopkins University urology fellow. Put another way, a recent rat study mens sexual health clinic Australia offers strong evidence that erectile dysfunction (ED) is more than just a bedroom bother. It may be ones own natural biomarker for coronary artery disease. And vigorous exercise can eliminate it all at least in the (literal) short run. There have been a few previous cross-sectional studies that show that men who are physically active throughout their lives tend to develop ED at lower rates than those who are not, says Justin La Favor, lead author of the recent American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology study . However, I think we can safely say that this is the first study to demonstrate that exercise can completely prevent the harmful effects of a bad diet on sexual function. Obesity, a worldwide plague, is often caused by the Western (aka junk food) diet of saturated fat, omega-6 polyunsaturated fatty acids and added sugar. Science has long known the Western diet can cause both ED and heart disease. Science has also long known exercise can stave off Western diet-induced heart disease. Could it also stave off Western diet-induced ED?
For the original version including any supplementary images or video, visit http://www.biosciencetechnology.com/articles/2013/09/erectile-dysfunction-biomarker-heart-disease
Fixing Erectile Dysfunction May Mask More Serious Problems
SERUM BIOMARKERS OF ENDOTHELIAL FUNCTION AND OXIDATIVE STRESS AFTER DAILY DOSING OF SILDENAFIL IN TYPE 2 DIABETIC MEN WITH ERECTILE DYSFUNCTION It is known that erectile dysfunction (ED), particularly in diabetic men, is often characterized by increased oxidative stress and decreased endothelial function. Johns Hopkins researchers investigated whether daily long-term sildenafil treatment can provide vasculoprotective effects in these patients in a multi-center, randomized, double-blind, placebo-controlled two-arm study. Using a group of 300 men with documented ED and type 2 diabetes mellitus, researchers measured serum biomarkers for endothelial function (cyclic guanosine monophosphate, or cGMP) and oxidative stress (8 isoprostane). Inflammatory cytokines were measured using Bio-Plex suspension array sytem assays for interleukin-6 and interleukin-8. Erectile dysfunction was measured based on affirmative responses to question 4 of the Sexual Health Inventory-Male which asks about a patients ability to maintain an erection for sexual intercourse. Endothelial function increased and oxidative stress decreased in the treatment group with no significant change noted in the placebo group. Erectile function improved in the treatment group with 22.8 percent at baseline and 58.2 percent at four weeks. Statistically significant change was not observed in the placebo group with 27.8 percent at baseline vs 30.7 percent at four weeks. BODY MASS INDEX AFFECTS THE RESPONSE TO SILDENAFIL IN MEN WITH MODERATE AND SEVERE LOWER URINARY TRACT SYMPTOMS A known link has been established between erectile dysfunction (ED) and cardiovascular risk factors such as obesity.
For the original version including any supplementary images or video, visit http://www.science20.com/news_articles/fixing_erectile_dysfunction_may_mask_more_serious_problems-1774