For the past several years, elixirs for boosting testosterone levels have been widely touted for curing low sex drives amid controversy over their benefits and research suggesting the malady is less common that advertising suggests. Now, though, a new study finds that the drugs raised the risk of a heart attack, stroke or death by 29 percent. Last year, AbbVies ( ABBV ) AndroGel sales totaled nearly $1.2 billion, a 32 percent rise, making the gel the second-biggest seller for the drugmaker behind the Humira rheumatoid arthritis treatment, which had sales of more than $9 billion. AbbVie stock is up about 40% year-to-date, since being spun off by Abbott ( ABT ). ABBV data by YCharts A topical solution called Axiron is sold by Eli Lilly ( LLY ) and Actavis ( ACT ) sells the Androderm patch. The study, which was published in the Journal of the American Medical Association, reviewed data from more than 8,700 men who underwent an angiography at one of 76 cardiac catheterization labs in the US Veterans Affairs health system between 2005 and 2011. Their average was in the early 60s and many had underlying illnesses, including prior heart attacks, diabetes and high blood pressure. Nearly 26 percent of the men using a testosterone gel, patch or injection had an adverse outcome within three years, compared with nearly 20 percent of those who did not use testosterone. It was unclear, though, how testosterone may increase heart risks, but possibilities include evidence that testosterone may affect blood platelets and lead to clots, atherosclerosis or coronary plaque.
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Treat Low Testosterone and Progesterone Deficiencies with Bioidentical Hormone Replacement Creams from TestoMeds
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5-Alpha-Reductase Deficiency Medication
Many pharmaceutical hormones produced by other suppliers are not bioidentical, but are actually synthetic analogues that may have some similar effects as bioidentical hormones, but are not identical to them. Synthetic testosterone analogues do not have as wide a spectrum of effects as TestoMeds' bioidentical testosterone. Synthetic analogues generally produce stronger, unnatural anabolic effects, which can bring about unwanted side effects on the skin, testes, and liver compared to TestoMeds' safe to use bioidentical hormone testosterone. TestoMeds has three highly effective, yet discount priced bioidentical products to significantly boost hormone levels: Androforte cream to treat low testosterone symptoms in men and Androfeme to treat testosterone deficiency in women. A third product line, Profeme, treats progesterone deficiency in women. AndroForte Testosterone Cream for Men (which comes in two percent and five percent formulas) is so effective that it only needs to applied once daily in small doses, unlike other most other creams that require heavy application or oral forms of testosterone supplements, which are taken in much higher, more intense dosage.
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Testosterone Not the Whole Story in 'Male Menopause'
And it's more complicated than those ads about "low T" and testosterone supplements might lead men to believe. Instead, researchers found, there is no black-and-white cutoff for "low" or "suboptimal" testosterone. Different symptoms crop up at different testosterone thresholds: Muscle mass and strength do not decline until testosterone drops quite low, whereas libido may dampen with relatively small dips in the hormone. "The question that patients always have is, 'What's a normal testosterone level?'" said Dr. John Amory, a professor of medicine at the University of Washington in Seattle, who was not involved in the study. "Well, now I'm going to ask, 'What endpoint are you talking about?'" Amory said. "Different functions of testosterone start to deteriorate at different levels." What's more, the study shows that men's functioning can be impaired http://www.mhcaustralia.com.au/slide-view/erectile-dysfunction/ not only by a loss of testosterone, but estrogen as well, according to lead researcher Dr.
For the original version including any supplementary images or video, visit http://consumer.healthday.com/general-health-information-16/misc-drugs-news-218/testosterone-not-the-whole-story-in-male-menopause-680065.html